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unexampled    
a. 无前例的,无可比拟的

无前例的,无可比拟的

unexampled
adj 1: having no previous example or precedent or parallel; "a
time of unexampled prosperity" [synonym: {new}, {unexampled}]

Unexampled \Unexampled\
See {exampled}.


Unexampled \Un`ex*am"pled\, a.
Having no example or similar case; being without precedent;
unprecedented; unparalleled. "A revolution . . . unexampled
for grandeur of results." --De Quincey.
[1913 Webster]


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  • Alectinib in Resected ALK-Positive Non–Small-Cell Lung Cancer
    Platinum-based chemotherapy is the recommended adjuvant treatment for patients with resectable, ALK-positive non–small-cell lung cancer (NSCLC) Data on the efficacy and safety of adjuvant
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    Alectinib targets cancer cells that have specific changes, called rearrangements, in the ALK gene The drug has been shown to increase how long people with ALK-positive metastatic NSCLC live and has become a mainstay for treatment of people with this form of lung cancer
  • FDA approves alectinib as adjuvant treatment for ALK-positive . . .
    FDA approves alectinib as adjuvant treatment for ALK-positive non-small cell lung cancer
  • Disease characteristics and treatment outcomes in patients . . .
    This exploratory analysis investigated whether the disease-free survival (DFS) benefit seen with adjuvant alectinib versus chemotherapy in patients with resected, ALK -positive non-small cell lung cancer (NSCLC) from the phase III ALINA study (NCT03456076) was maintained across surgical characteristic subgroups and when re-classifying patients according to the 8th edition of the Cancer Staging
  • ALK and Lung Cancer - American Lung Association
    ALK stands for anaplastic lymphoma kinase It was originally described in lymphoma, but most ALK-positive cancers are in non-small cell lung cancer
  • Anaplastic lymphoma kinase (ALK)-positive advanced non-small . . .
    INTRODUCTION Anaplastic lymphoma kinase (ALK) is a tyrosine kinase that can be aberrantly expressed in several tumor types In non-small cell lung cancer (NSCLC), chromosomal rearrangements involving the ALK gene loci on chromosome 2 are found in approximately 3 to 5 percent of NSCLC tumors [1,2] The most common ALK rearrangement in NSCLC juxtaposes the 5' end of the echinoderm microtubule
  • ALK-positive lung cancer: what it means and targeted . . .
    What does ALK-positive in non-small cell lung cancer mean what are some treatment options? Georgetown University's Dr Stephen Liu shares insights
  • Novel Small Molecule Earns FDA Fast Track Designation in ALK+ . . .
    Investigators are currently evaluating treatment with TRI-611 among patients with ALK-positive non–small cell lung cancer in a phase 1 2 trial Investigators are currently evaluating the safety, pharmacokinetics, and preliminary activity of TRI-611 among patients with ALK-positive NSCLC as part of a phase 1 2 study (NCT07491497)
  • Alectinib in combination with bevacizumab as first-line . . .
    Up to 25% of patients with ALK-rearranged non-small cell lung cancer (NSCLC) experience disease progression within the first year of targeted therapy This work reports a phase 2 trial
  • Update 2025: Management of Non‑Small-Cell Lung Cancer - PMC
    Introduction Lung cancer has remained the leading cause of cancer-related mortality worldwide since the 1950s, posing a significant global health challenge [1] NSCLC, which constitutes the majority of lung cancer cases, has historically been associated with poor outcomes due to its often late diagnosis and limited treatment options [2]





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