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lactam

乳胺; 内酰胺

乳胺; 内□胺

The Collaborative International Dictionary of English v.0.48 (gcide)

Lactam \Lac"tam\, n. [Lactone amido.] (Chem.)
One of a series of anhydrides of an amido type, analogous to
the lactones, as oxindol; a cyclic amide.
[1913 Webster]

{beta-lactam} or {[beta]-lactam},
(a) a lactam in which the amide bond is contained within a
four-membered ring, which includes the amide nitrogen and
the carbonyl carbon.
(b) an antibiotic containing a beta-lactam, such as a
{penicillin}, {cephalosporin}, or {carbapenem}; also
called a {beta-lactam antibiotic}. [informal, laboratory
slang]
[PJC]

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英文字典中文字典相关资料:

Lactam - Wikipedia
A lactam is a cyclic amide, formally derived from an amino carboxylic acid through cyclization reactions [1] The term is a portmanteau of the words lactone + amide
LACTAM Definition Meaning | Merriam-Webster Medical
The meaning of LACTAM is any of a class of amides of amino carboxylic acids that are formed by the loss of a molecule of water from the amino and carboxyl groups, that are characterized by the carbonyl-imido group —CONH— in a ring, and that include many antibiotics
LACTAM Definition Meaning | Dictionary. com
LACTAM definition: any of a group of cyclic amides characterized by the NHCO group, derived from aminocarboxylic acids by the intramolecular elimination of water from the amino and carboxylic groups See examples of lactam used in a sentence
Lactam | chemical compound | Britannica
Other articles where lactam is discussed: carboxylic acid: Nomenclature: Cyclic amides are called lactams Their common names are derived in a manner similar to those of lactones, with the difference that the suffix -olactone is replaced by -olactam
β-Lactam - Wikipedia
The β-lactam ring is part of the core structure of several antibiotic families, the principal ones being the penicillins, cephalosporins, carbapenems, and monobactams, which are, therefore, also called β-lactam antibiotics
What is Lactam? - BYJUS
A four-atom ring known as alpha-lactam is present in all of these antibiotics’ molecular structures Antibiotics with alpha-lactams are used to prevent and cure bacterial infections caused by susceptible organisms
LACTAM definition and meaning | Collins English Dictionary
lactam in American English (ˈlækˌtæm ) noun Origin: lactone + amino any of a group of organic cyclic compounds containing the NHCO group in the ring, formed by the elimination of water from the amino and carboxyl groups; inner anhydride of an amino acid
Lactam - Chemistry LibreTexts
A lactam or cyclic amide is an amide in the molecule of which there are one or two carbon chains connecting the carbonyl carbon to the nitrogen atom
Synthesis and Reactions of Lactones and Lactams
They are key structural motifs in many biologically active compounds, including β-lactam antibiotics like penicillin and cephalosporins See the last row of this list of important nitrogen-containing compounds with biological and medical significance:
Beta-Lactam Alone Matches Combination Therapy in CAP - Medscape
Among patients hospitalized with community-acquired pneumonia (CAP), the addition of azithromycin to a beta-lactam antibiotic was not associated with improved clinical outcomes compared with beta

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